Randal Grichuk was 4-5 with a run scored and an RBI in a losing effort as the Blue Jays were edged by the Orioles 6-5
- The Orioles opened the scoring in the bottom of the 1st as Jace Pederson singled home Anthony Santander
- Jimmy Yacbonis pitching line: 1IP 1H 0R 2BB 0K 19 pitches (10 for strikes)
- The Blue Jays tied it in the top of the 2nd as Teoscar Hernandez singled scoring Randal Grichuk
- The Orioles retook the lead in the bottom half of the inning as Chance Sisco scored on a fielding error by Bo Bichette
- A batter later, Trey Mancini doubled scoring Chris Davis and Jonathan Villar
- The Blue Jays got a run back in the top of the 5th as Lourdes Gurriel Jr. scored on a ground out by Justin Smoak
- Sean Reid-Foley pitching line: 4IP 4H 4R (1 earned) 4BB 2K 81 pitches (46 for strikes)
- The Orioles added a run in the bottom of the 5th as Sisco drew a bases loaded walk forcing in Mancini
- A batter later, Davis drew a bases loaded walk forcing in Pederson
- The Blue Jays got one back in the top of the 7th as Bo Bichette smacked a solo blast to right-center
- A batter later, Cavan Biggio whacked a solo bomb to right
- Three batters later, Grichuk doubled scoring Vladimir Guerrero Jr.
- Shawn Armstrong pitched a scoreless 9th for his 4th save of the season
- Final score: Orioles 6 Blue Jays 5
- SRF had a rough start with zero command. He gave up 4 runs (just one that was earned thanks to a fielding error by Bo Bichette) on 4 hits, while walking 4 and striking out a pair. The Orioles are one of the weaker lineups in the league. Reid-Foley will face a much stiffer test next week at home against the Yankees
- Randal Grichuk had a very strong day at the plate with a 4-5 effort, a run scored and an RBI. Bo Bichette (2-5, solo HR), Vladimir Guerrero Jr. (3-5, run scored) and Teoscar Hernandez (2-5, RBI) also had good days at the plate. Although, Teo struck out to end the game
- Yennsy Diaz had a very rough MLB debut, walking 4, allowing one hit and 2 runs (both on bases loaded walks) in 0.2 innings.
- Up next, the Blue Jays head to Tampa Bay to meet ex-teammate Eric Sogard and the Rays. Jacob Waguespack will start the opener against Rays righty Charlie Morton.